MCQs On Molecular Basis Of Inheritance

MCQs On Molecular Basis Of Inheritance

1. The nucleic acid synthesis takes place in

1. 3’-5’ direction
2. 5’-3’ direction
3. Both ways
4. Any direction

2. What is the nature of the strands of the DNA duplex?

1. Anti-parallel and complementary
2. Identical and complementary
3. Anti=parallel and non-complementary
4. Dissimilar and non-complementary

3. Hershey and Chase’s experiment was based on the principle

1. Transformation
2. Translation
3. Transduction
4. Transcription

4. AUG stands for

1. Alanine
2. Methionine
3. N-formyl methionine
4. Glycine

5. The reason behind the anti-parallel strand of DNA is

1. Hydrogen bond
2. Ionic bond
3. Phosphodiester bond
4. Disulphide bond

6. In a transcription unit, the promoter is located towards

1. 5’end of the structural gene
2. 3’end of the structural gene
3. 5’end of the template strand
4. 3’end of the coding strand

7. The primer in DNA replication is

1. Small ribonucleotide polymer
2. Helix destabilizing protein
3. Small deoxyribonucleotide polymer
4. Enzyme joining nucleotides of new strands

8. Genetic information is transferred from nucleus to cytoplasm through

1. RNA
2. Anticodon
3. DNA
4. Lysosomes

9. The enzyme involved in transcription

1. DNA Polymerase I
2. DNA Polymerase III
3. RNA Polymerase
4. DNA Polymerase II

10. Non-sense codons participate in

1. Releasing t-RNA from polynucleotide chain
2. Formation of unspecified amino acids
3. Terminating message of gene-controlled protein synthesis
4. Conversion of sense DNA into non-sense DNA

11. The proofreading enzyme in DNA replication is

1. Primase
2. DNA Polymerase I
3. Ligase
4. DNA Polymerase II

12. Select a ribozyme

1. Peptidyl transferase
2. Helicase
3. Ribonuclease-P
4. Both (a) and (c)

13. Which step does not occur in translation?

1. Replication
2. Termination
3. Elongation
4. Initiation

14. Select the incorrectly matched pairs

1. Purines – Nitrogenous bases cytosine, thymine and uracil
2. Recombinant DNA – DNA formed by joining the DNA segments from two different sources
3. rRNA – RNA found in ribosomes
4. ATP – The energy-carrying compound in the cell

15. The energy source for the elongation process is

1. Creatine-PO₄
2. GTP
3. ATP
4. All of the above

16. The anticodon of initiation codon for protein synthesis is

1. UUU
2. AUG
3. UAC
4. CAU

17. In lac-operon, which protein is not regulated by the repressor?

1. Galactosidase
2. Lactose Permease
3. Tryptophan
4. Transacetylase

18. Which enzyme is not produced during lactose catabolism by E.coli?

1. ????-galactosidase
2. Lactose Permease
3. Thiogalactoside transacetylase
4. Lactose dehydrogenase

19. The eukaryotic replication of DNA is

1. Bidirectional with many origins
2. Unidirectional with many origins
3. Bidirectional with a single origin
4. Unidirectional with a single origin

20. The amino acid coded by 3 codons is

1. Proline
2. Isoleucine
3. Tryptophan
4. Serine

21. Spliceosomes are absent in the cells of

1. Plants
2. Animals
3. Bacteria
4. Fungi

22. A molecule that acts as a genetic material must fulfil the following traits, except

1. It should be structurally and chemically unstable
2. It should have the ability to generate its replica
3. It should facilitate slow changes necessary for evolution.
4. It should be able to express itself in the form of Mendelian characters.

23. What will the amount of guanine in a DNA if the total amount of adenine and thiamine in the DNA is 45%?

1. 45%
2. 65%
3. 27.5%
4. 22.3%

24. The primary control of gene expression takes place at the level of

1. Translation
2. Replication
3. Transcription
4. None

25. The gene sequence that codes for proteins are

1. Exons
2. Introns
3. Intervening sequences
4. Control regions

26. The process of RNA splicing shows the dominance of

1. RNA world
2. DNA world
3. Microbial world
4. Protein world

27. In eukaryotes, RNA II facilitates transcription of

1. rRNA
2. mRNA
3. hnRNA
4. tRNA

28. Human Genome Project led to the development of

1. Biotechnology
2. Bioinformatics
3. Biosystematics
4. Bioengineering

29. Which non-radioactive isotope was used by Messelson and Stahl in their experiment?

1. P32
2. S35
3. N15
4. None

30. Histones are

1. Positively charged and basic amino acids
2. Positively charged and acidic proteins
3. Negatively charged and basic proteins
4. Absent in bacteria

Answer Key

1-2	2-1	3-3	4-2	5-3	6-1	7-1	8-1	9-3	10-3
11-2	12-4	13-1	14-1	15-2	16-3	17-3	18-4	19-1	20-2
21-3	22-1	23-3	24-3	25-1	26-1	27-3	28-2	29-3	30-4