Chapter 22: Chemical Coordination and Integration – MCQs with Answers & Explanations

CBSE Class 11 Biology MCQs – Chemical Coordination and Integration (NCERT)

Course & Examination Details

• Course: CBSE Class 11 Biology
• Prescribed By: Central Board of Secondary Education
• Based On: NCERT
• Unit: Unit V – Human Physiology
• Chapter: Chapter 22 – Chemical Coordination and Integration
• Question Type: Multiple Choice Questions (MCQs)
• Exam Relevance: CBSE Class 11 Annual Exam, Unit Tests, Periodic Assessments

Section A: Endocrine Glands (MCQ 1–20)

1. Chemical coordination in humans is carried out by

A. Nervous system
B. Muscular system
C. Endocrine system
D. Digestive system

Correct Answer: C
Explanation:
Chemical coordination is achieved by hormones secreted by endocrine glands.

2. Endocrine glands are characterized by

A. Presence of ducts
B. Local action
C. Ductless nature
D. Secretion of enzymes

Correct Answer: C
Explanation:
Endocrine glands lack ducts and release hormones directly into blood.

3. The master gland of the endocrine system is

A. Thyroid
B. Adrenal
C. Pituitary
D. Hypothalamus

Correct Answer: C
Explanation:
Pituitary regulates the activity of other endocrine glands.

4. The pituitary gland is located

A. In neck
B. Above hypothalamus
C. Below hypothalamus
D. In thoracic cavity

Correct Answer: C
Explanation:
Pituitary lies below hypothalamus at the base of brain.

5. Which gland links nervous and endocrine systems?

A. Pituitary
B. Thyroid
C. Hypothalamus
D. Pineal

Correct Answer: C
Explanation:
Hypothalamus integrates neural and hormonal coordination.

6. Hormone regulating circadian rhythm is

A. Thyroxine
B. Melatonin
C. Cortisol
D. Adrenaline

Correct Answer: B
Explanation:
Melatonin controls sleep–wake cycle.

7. Melatonin is secreted by

A. Pituitary
B. Pineal
C. Thyroid
D. Adrenal

Correct Answer: B
Explanation:
Pineal gland secretes melatonin.

8. Thyroid hormones regulate

A. Water balance
B. Calcium balance
C. Basal metabolic rate
D. Blood glucose

Correct Answer: C
Explanation:
Thyroxine regulates basal metabolic rate.

9. Iodine deficiency leads to

A. Diabetes
B. Tetany
C. Goitre
D. Cushing’s syndrome

Correct Answer: C
Explanation:
Iodine deficiency causes enlargement of thyroid gland.

10. Parathyroid hormone regulates

A. Blood glucose
B. Sodium balance
C. Calcium balance
D. Water balance

Correct Answer: C
Explanation:
PTH maintains calcium and phosphate levels.

11. Adrenal glands are called emergency glands because they secrete

A. Thyroxine
B. Cortisol
C. Adrenaline
D. Aldosterone

Correct Answer: C
Explanation:
Adrenaline prepares body for stress.

12. Adrenaline causes

A. Decrease in heart rate
B. Decrease in blood pressure
C. Increase in heart rate
D. Decrease in glucose level

Correct Answer: C
Explanation:
Adrenaline increases heart rate and blood pressure.

13. The adrenal gland has

A. One part
B. Two parts
C. Three parts
D. Four parts

Correct Answer: B
Explanation:
Adrenal gland has cortex and medulla.

14. Pancreas is a

A. Exocrine gland
B. Endocrine gland
C. Heterocrine gland
D. Ductless gland only

Correct Answer: C
Explanation:
Pancreas has both endocrine and exocrine functions.

15. Endocrine part of pancreas is

A. Acini
B. Ducts
C. Islets of Langerhans
D. Pancreatic juice

Correct Answer: C
Explanation:
Islets secrete insulin and glucagon.

16. Insulin is secreted by

A. Alpha cells
B. Beta cells
C. Delta cells
D. Acinar cells

Correct Answer: B
Explanation:
Beta cells of islets secrete insulin.

17. Testosterone is secreted by

A. Ovaries
B. Adrenal cortex
C. Testes
D. Pituitary

Correct Answer: C
Explanation:
Testes secrete testosterone.

18. Estrogen and progesterone are secreted by

A. Pituitary
B. Testes
C. Ovaries
D. Adrenal

Correct Answer: C
Explanation:
Ovaries secrete female sex hormones.

19. Oxytocin helps in

A. Milk production
B. Milk ejection
C. Growth
D. Ovulation

Correct Answer: B
Explanation:
Oxytocin causes milk ejection and uterine contraction.

20. ADH mainly regulates

A. Blood glucose
B. Calcium balance
C. Water balance
D. Metabolism

Correct Answer: C
Explanation:
ADH controls water reabsorption in kidneys.

Section B: Hormones & Mechanism of Action (MCQ 21–35)

21. Hormones are

A. Nutrients
B. Enzymes
C. Chemical messengers
D. Structural proteins

Correct Answer: C
Explanation:
Hormones act as chemical messengers.

22. Hormones are effective in

A. Large quantities
B. Moderate quantities
C. Minute quantities
D. Unlimited quantities

Correct Answer: C
Explanation:
Hormones act effectively in small amounts.

23. Hormone specificity depends on

A. Blood flow
B. Target organ size
C. Presence of receptors
D. Hormone concentration

Correct Answer: C
Explanation:
Only cells with receptors respond.

24. Steroid hormones are

A. Water-soluble
B. Lipid-soluble
C. Proteinaceous
D. Enzymatic

Correct Answer: B
Explanation:
Steroid hormones dissolve in lipids.

25. Water-soluble hormones act through

A. Gene expression
B. Second messengers
C. Ribosomes
D. Mitochondria

Correct Answer: B
Explanation:
They act via cAMP and other messengers.

26. Second messenger commonly involved is

A. DNA
B. RNA
C. cAMP
D. ATP

Correct Answer: C
Explanation:
cAMP mediates hormone action.

27. Lipid-soluble hormones act by

A. Activating enzymes directly
B. Binding membrane receptors
C. Altering gene expression
D. Acting as neurotransmitters

Correct Answer: C
Explanation:
They influence transcription and translation.

28. Target organ means

A. Gland secreting hormone
B. Tissue producing hormone
C. Tissue responding to hormone
D. Tissue storing hormone

Correct Answer: C
Explanation:
Target organ responds to hormone.

29. Basal metabolic rate is regulated by

A. Insulin
B. Thyroxine
C. Adrenaline
D. ADH

Correct Answer: B
Explanation:
Thyroxine controls metabolic rate.

30. Growth hormone deficiency in childhood causes

A. Acromegaly
B. Gigantism
C. Dwarfism
D. Goitre

Correct Answer: C
Explanation:
GH deficiency causes dwarfism.

31. Excess growth hormone in adults causes

A. Dwarfism
B. Gigantism
C. Acromegaly
D. Cretinism

Correct Answer: C
Explanation:
Acromegaly occurs in adults.

32. Feedback mechanism mostly involved in endocrine regulation is

A. Positive feedback
B. Neutral feedback
C. Negative feedback
D. Random feedback

Correct Answer: C
Explanation:
Negative feedback maintains balance.

33. Thyroxine inhibits secretion of

A. ACTH
B. TSH
C. FSH
D. GH

Correct Answer: B
Explanation:
Thyroxine inhibits TSH release.

34. Insulin and glucagon act

A. Synergistically
B. Independently
C. Antagonistically
D. Sequentially

Correct Answer: C
Explanation:
They have opposite effects.

35. Insulin lowers blood glucose by

A. Glycogen breakdown
B. Glucose synthesis
C. Glucose uptake
D. Fat breakdown

Correct Answer: C
Explanation:
Insulin promotes glucose uptake and storage.

Section C: Hormonal Disorders (MCQ 36–50)

36. Diabetes mellitus is caused by deficiency of

A. Thyroxine
B. ADH
C. Insulin
D. Cortisol

Correct Answer: C
Explanation:
Insulin deficiency causes diabetes mellitus.

37. Excess glucose in urine is called

A. Ketosis
B. Glycosuria
C. Polyuria
D. Polydipsia

Correct Answer: B
Explanation:
Glucose in urine is glycosuria.

38. Diabetes insipidus is due to deficiency of

A. Insulin
B. Thyroxine
C. ADH
D. Cortisol

Correct Answer: C
Explanation:
ADH deficiency causes diabetes insipidus.

39. Goitre is enlargement of

A. Pituitary
B. Thyroid
C. Adrenal
D. Pancreas

Correct Answer: B
Explanation:
Thyroid gland enlarges in goitre.

40. Hypothyroidism in adults causes

A. Cretinism
B. Myxedema
C. Acromegaly
D. Tetany

Correct Answer: B
Explanation:
Myxedema occurs in adults.

41. Hypothyroidism in children causes

A. Myxedema
B. Cretinism
C. Goitre
D. Addison’s disease

Correct Answer: B
Explanation:
Cretinism occurs in children.

42. Excess cortisol leads to

A. Addison’s disease
B. Tetany
C. Cushing’s syndrome
D. Diabetes insipidus

Correct Answer: C
Explanation:
Cushing’s syndrome results from cortisol excess.

43. Addison’s disease is due to deficiency of

A. Thyroid hormones
B. Adrenal hormones
C. Pancreatic hormones
D. Pituitary hormones

Correct Answer: B
Explanation:
Adrenal hormone deficiency causes Addison’s disease.

44. Low calcium level causes

A. Goitre
B. Tetany
C. Acromegaly
D. Gigantism

Correct Answer: B
Explanation:
Tetany is due to low calcium.

45. Tetany is caused by deficiency of

A. Thyroxine
B. Insulin
C. PTH
D. ADH

Correct Answer: C
Explanation:
PTH deficiency lowers calcium.

46. Cushing’s syndrome shows

A. Weight loss
B. Muscle wasting
C. Obesity
D. Short stature

Correct Answer: C
Explanation:
Cortisol excess causes obesity.

47. Hormonal imbalance mainly affects

A. Short-term responses
B. Long-term regulation
C. Digestion only
D. Respiration only

Correct Answer: B
Explanation:
Hormones regulate long-term processes.

48. Hormonal coordination is slow because

A. Hormones are inactive
B. Hormones travel in blood
C. Hormones are enzymes
D. Hormones act locally

Correct Answer: B
Explanation:
Blood transport makes response slower.

49. Which hormone maintains pregnancy?

A. Estrogen
B. Progesterone
C. FSH
D. LH

Correct Answer: B
Explanation:
Progesterone maintains pregnancy.

50. Chemical coordination is essential for

A. Reflex action
B. Long-term growth
C. Instant response
D. Muscle contraction only

Correct Answer: B
Explanation:
Hormones regulate growth and development.

NCERT & CBSE Compliance Note

✔ Strictly based on NCERT Class 11 Biology
✔ Concept-clearing explanations included
✔ Framework-aligned and exam-oriented
✔ Ideal for CBSE Class 11 board examinations

🎯 Targeting Exams

This MCQ set is highly useful for preparation of:

• CBSE Class 11 Biology Annual Examination

• CBSE Unit Tests & Periodic Assessments

• NEET (UG) – Human Physiology & Endocrine System

• CUET (UG) – Biology Section

• State Board Class 11 Biology Exams

• Medical & Paramedical Entrance Foundation Courses

🔑 Related & Semantic Keyphrases

• Chemical Coordination and Integration MCQs Class 11

• CBSE Class 11 Biology Chapter 22 MCQs

• NCERT Chemical Coordination and Integration MCQs

• Endocrine Glands MCQs Class 11

• Hormones and Hormonal Disorders MCQs

• Human Endocrine System MCQs NCERT

• Class 11 Biology Objective Questions Human Physiology